The College of Glycation is an educational video series dedicated to helping viewers understand one of the most critical and often overlooked processes in human biology: glycation. Led by Dr. Paul Reynolds, Professor of Cell Biology and Physiology at Brigham Young University, this series explores how sugar interacts with proteins and fats in the body, forming harmful compounds called Advanced Glycation End-products (AGEs). These compounds accelerate aging, contribute to chronic diseases, and play a key role in metabolic dysfunction. Each video is designed to break down complex topics into clear, practical insights. Whether you’re a healthcare professional, student, or simply someone seeking to improve your health, this series will give you a deeper understanding of the biological roots of inflammation, insulin resistance, and cellular damage—and what you can do to address them.
Curated by: PaulReynoldsPhD (74 videos)
In this foundational lecture for the College of Glycation, Dr. Paul Reynolds explores oxidative stress—a silent force behind aging, chronic inflammation, and numerous modern diseases. He breaks down how oxidative stress arises when reactive oxygen species (ROS) overwhelm the body’s antioxidant defenses, damaging proteins, DNA, and cells. Through historical insights, cutting-edge research, and practical examples, Dr. Reynolds explains what oxidative stress is, how our diets and lifestyles accelerate it, and what we can do to protect ourselves. This episode empowers viewers with an accessible, evidence-based guide to managing oxidative stress and enhancing long-term health. Timestamps: 00:00 – Intro: What is Oxidative Stress? 00:38 – Why It Matters for Aging & Disease 01:18 – Brief History & Scientific Roots 02:00 – ROS, Mitochondria & Antioxidants 03:24 – Triggers: Diet, Stress, Environment 04:06 – High Glucose, Carbs & ROS 05:32 – Seed Oils, Cortisol & Inactivity 07:00 – Ketosis as a Defense 07:42 – Human Evidence on Keto Benefits 08:24 – Oxidative Stress in Major Diseases 10:32 – How to Fight Back: Diet & Lifestyle 11:14 – Exercise, Sleep & Antioxidant Foods 12:37 – Final Thoughts: Take Control Topics Covered -The biology of oxidative stress and the role of reactive oxygen species (ROS) -The origins of the free radical theory of aging and its modern scientific foundation -How oxidative stress contributes to chronic diseases like heart disease, diabetes, Alzheimer’s, and cancer -The relationship between high-carbohydrate diets, glycation, and ROS production -The benefits of ketosis and low-carb diets in reducing oxidative damage -Actionable strategies to fight oxidative stress through diet, exercise, sleep, and stress management About Dr. Paul Reynolds Dr. Paul Reynolds is a Professor of Cell Biology and Physiology at Brigham Young University. With a gift for making complex biomedical concepts easy to grasp, he combines research-based teaching with practical lifestyle guidance. Through the College of Glycation series, Dr. Reynolds aims to help audiences understand and apply the science of inflammation, metabolism, and chronic disease prevention. For more science-backed insights on glycation, oxidative stress, and metabolic health, subscribe and continue learning with the College of Glycation series. Questions? Leave a comment below. #CollegeOfGlycation #DrPaulReynolds #OxidativeStress #FreeRadicals #Antioxidants #ChronicDisease #LowCarb #Ketosis #Healthspan #MetabolicHealth #AntiAging #SciencePodcast #CellBiology #HealthyLiving #AGEs #BloodSugar #KetoDiet #Wellness #healtheducation Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3 Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount. Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20) Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)