The College of Glycation is an educational video series dedicated to helping viewers understand one of the most critical and often overlooked processes in human biology: glycation. Led by Dr. Paul Reynolds, Professor of Cell Biology and Physiology at Brigham Young University, this series explores how sugar interacts with proteins and fats in the body, forming harmful compounds called Advanced Glycation End-products (AGEs). These compounds accelerate aging, contribute to chronic diseases, and play a key role in metabolic dysfunction. Each video is designed to break down complex topics into clear, practical insights. Whether you’re a healthcare professional, student, or simply someone seeking to improve your health, this series will give you a deeper understanding of the biological roots of inflammation, insulin resistance, and cellular damage—and what you can do to address them.
Curated by: PaulReynoldsPhD (79 videos)
Topic Natural GLP-1: why “Nature’s Ozempic” foods cannot copy a weekly agonist — and why flattening the postprandial glucose curve still matters for glycation. Quick summary Food can raise your own GLP-1. It cannot copy semaglutide. Native GLP-1 is a meal-timing signal with a functional half-life of a couple of minutes; the drugs are built to resist DPP-4 and last about a week. What the so-called natural boosters actually do well is slower and more valuable for this show: they flatten the glucose curve. Viscous fiber (oat beta-glucan, psyllium, chia gel) delays gastric emptying even when GLP-1 itself does not move. Eating protein and vegetables before starch does the same and does raise GLP-1. Fermentable fiber, bitter compounds such as berberine, and olive oil work through slower or separate receptors. A flatter curve means less glucose in contact with protein for less time — fewer Amadori products and less AGE burden in tissues that cannot be replaced. Use the tools. Do not sell them as a natural version of the drug. For complete show notes and references Become an Insider subscriber for the enhanced summary, timestamps, and links to every cited publication, plus the weekly newsletter, early episode access, the question portal, and Paul’s Weekly Research Review. Learn more: https://paulreynoldsphd.com Translation notes Click the gear icon at the bottom of this video to auto-translate captions. For French, for example: Subtitles → Auto-Translate → English first → Auto-Translate again → French. Note The information presented is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Paul Reynolds is a biomedical scientist and professor of cell biology, not a licensed clinician. Always seek the advice of your own qualified health providers with questions you may have regarding medical conditions. #GLP1 #ViscousFiber #GastricEmptying #MealSequencing #DPP4 #insulinresistance #Glycation #AGEs #inflammation #OxidativeStress #ROS #Redox #CollegeOfGlycation #Ketodiet #LowCarb #InsulinResistance #HealthyAging #SugarDamage #HealthyLiving #KetoDiet #LowCarb #HealthPodcast #AntiAging #Nutrition #BiomedicalScience #BloodSugar #Wellness #HealthTips #SciencePodcast #HealthyEating #CellularHealth #Keto #KetoCommunity #HealthEducation Paul’s favorite yerba mate: https://unicity.link/121f260bfe Yerba mate with a special formulated Balance fiber: https://ufeelgreat.com/c/PaulReynolds For the full Metabolic System storefront: https://shop.unicity.com/paulreynolds Paul’s favorite source for clean, earth-sourced essentials such as salt, electrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount. Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)