The College of Glycation is an educational video series dedicated to helping viewers understand one of the most critical and often overlooked processes in human biology: glycation. Led by Dr. Paul Reynolds, Professor of Cell Biology and Physiology at Brigham Young University, this series explores how sugar interacts with proteins and fats in the body, forming harmful compounds called Advanced Glycation End-products (AGEs). These compounds accelerate aging, contribute to chronic diseases, and play a key role in metabolic dysfunction. Each video is designed to break down complex topics into clear, practical insights. Whether you’re a healthcare professional, student, or simply someone seeking to improve your health, this series will give you a deeper understanding of the biological roots of inflammation, insulin resistance, and cellular damage—and what you can do to address them.
Curated by: PaulReynoldsPhD (74 videos)
In this second foundational lecture from the College of Glycation, Dr. Paul Reynolds unpacks the biology of inflammation—a vital but misunderstood process at the root of nearly every chronic disease. From twisted ankles to heart disease and Alzheimer’s, inflammation can be both a healing force and a hidden saboteur. With historical insight and cutting-edge research, Dr. Reynolds explores the difference between acute and chronic inflammation, how our modern lifestyle fuels the fire, and why controlling it is critical to long-term health. You’ll learn the cellular mechanisms that trigger inflammation, how dietary choices like refined carbs and seed oils contribute, and how powerful strategies like ketosis, exercise, and mindfulness can help extinguish the flames. Whether you’re managing a chronic condition or simply curious about optimizing your health, this lecture delivers a clear, evidence-based path to understanding and taming the inflammation epidemic. Timestamps: 00:00 – Intro to the College of Glycation 00:36 – Why Inflammation Matters 01:12 – Historical Overview 02:31 – What Is Inflammation? 03:07 – Cellular Mechanics & Cytokines 04:25 – The NF-κB Pathway & Human Studies 05:08 – Acute Inflammation: The Body’s Superpower 06:23 – Chronic Inflammation Explained 07:05 – Cell & Human Evidence of Chronic Inflammation 08:23 – Lifestyle & Diet as Root Causes 09:42 – Sugar, Carbs & Inflammation 10:24 – Seed Oils & Omega-6 Fats 11:10 – Stress, Sleep, and Sedentary Lifestyle 11:53 – Ketosis: Anti-Inflammatory Effects 13:11 – Inflammation in Chronic Disease 14:31 – Solutions: Mediterranean Diet & Omega-3s 15:14 – Exercise as Medicine 15:55 – Sleep, Cortisol & Stress 16:35 – Mindfulness & Parasympathetic Balance 17:14 – Conclusion & Key Takeaways Topics Covered -The biology of inflammation and its dual role in healing and harm -Key historical discoveries in inflammation science -How acute inflammation protects us—and why chronic inflammation damages us -The cellular and molecular players: cytokines, NF-kappaB, and more -Why modern diets (refined carbs, seed oils) are major inflammation drivers -The anti-inflammatory power of ketosis and low-carbohydrate diets -Evidence-based lifestyle interventions: diet, movement, sleep, stress reduction About Dr. Paul Reynolds Dr. Paul Reynolds is a Professor at Brigham Young University and a biomedical scientist dedicated to making complex health science accessible. Through the College of Glycation series, he demystifies metabolic health, helping viewers understand the biochemical forces shaping their well-being—and how to take control. Subscribe for future lectures on glycation, inflammation, and cellular health, and join the growing community focused on evidence-based strategies for a longer, healthier life. #CollegeOfGlycation #DrPaulReynolds #Inflammation #MetabolicHealth #Ketosis #LowCarb #HealthScience #AntiAging #ChronicDisease #WellnessEducation #biomedicalresearch Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3 Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount. Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20) Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)