The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works. Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.
Curated by: Andrew Huberman (417 videos)
In this Huberman Lab Essentials episode, I explain the biology, symptoms and types of bipolar disorder (sometimes called bipolar depression), a condition characterized by extreme, maladaptive shifts in energy, mood and perception. I describe the diagnostic criteria that distinguish bipolar I from bipolar II, including mania and hypomania and the different patterns of mood cycling. I discuss the remarkable history and discovery of lithium and how it works, in part by reducing inflammation, providing neuroprotection and supporting the interoceptive neural circuits affected in bipolar disorder. I also cover talk therapies, electroconvulsive therapy and nutraceuticals such as omega-3 fatty acids and inositol, and I explore the intriguing relationship between mood disorders and creativity. This episode should interest anyone who has or knows someone with bipolar disorder, as well as those interested in how the brain balances mood, energy and focus. Show notes: https://go.hubermanlab.com/wH7DHIu Watch more Huberman Lab Essentials: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S&si=a1_sA7rUT-fE0OM5 Follow Huberman Lab Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://x.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Timestamps 00:00:00 Bipolar Disorder 00:01:09 Bipolar I; Manic Episode Symptoms 00:05:00 Bipolar II, Hypomania; Depressive Episodes & Cycling 00:07:30 Lithium Discovery, Dr. John Cade, Uric Acid 00:11:03 Lithium Urate & Guinea Pigs, Control Experiments 00:13:20 Lithium Salts Paper, Toxicity & Monitoring 00:14:30 How Lithium Works: Inflammation & Neuroprotection 00:15:50 Exteroception vs. Interoception, Neural Circuit Atrophy 00:17:31 Drug vs. Talk Therapies 00:18:10 Cognitive Behavioral Therapy, Interpersonal & Social Rhythm Therapy 00:20:00 Electroconvulsive Therapy (ECT), Treatment-Resistant Depression 00:21:37 Caution: Rely on Prescribed Treatment, Suicide Risk 00:22:29 Tool: Lifestyle Support, Sleep, Exercise, Nutrition & Sunlight 00:23:30 Tool: Inositol & Omega-3 Fatty Acids, Fish Oil Study 00:25:30 Full Picture of Treatment 00:26:40 Creativity & Mood Disorders, Eminent Individuals Study 00:30:00 Recap & Key Takeaways #hubermanlab #science #health Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer