The Metabolic Classroom

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Curated by: Ben Bikman (139 videos)


Currently Playing: 124: How Ketones Help the Brain Recover From Concussions with Dr. Ben Bikman

📢 Ask Dr. Bikman’s Digital Mind: https://benbikman.com/ben-bikmans-digital-ai-mind 📢 Dr. Bikman’s Community & Coaching Site, Insulin IQ: https://insuliniq.com 📢 Become an Insider, Ben’s website: https://www.benbikman.com In this mini lecture Dr. Bikman explores how concussions cause more than just structural damage to the brain—they create a serious metabolic energy crisis. A concussion reduces the brain’s ability to use glucose by impairing glucose transporters and glycolytic enzymes, leaving neurons starved for energy just when demand spikes. This disruption persists even after initial symptoms fade and can worsen inflammation and oxidative stress, further harming brain function. Fortunately, ketones provide a powerful alternative energy source. Unlike glucose, ketones can bypass the damaged pathways and fuel the brain directly via mitochondria, improving ATP production, reducing oxidative stress, and modulating inflammation. Both ketogenic diets and exogenous ketones (like goBHB) can dramatically improve brain recovery after a concussion and even provide preventative protection for athletes and others at risk of head injuries. Animal and limited human studies confirm that after injury, the brain increases its ability to use ketones, especially when they are available immediately. Studies show improvements in mitochondrial function, reduced lesion volume, and even increased neuroplasticity and antioxidant gene expression. Whether through fasting, dietary restriction, or supplementation, making ketones available may be a crucial part of supporting the injured brain. Show Notes/References: For complete show notes and references, we invite you to become an Insider subscriber or member. You’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben after the lecture, unlimited access to Dr. Bikman’s Digital Mind, ad-free podcast episodes, show notes and references, and online, live Office Hours access with Ben. It also includes Ben’s Weekly Research Review Podcast, and a searchable archive. Learn more: https://www.benbikman.com Translation Notes: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.) Also, Dr. Bikman’s Digital Mind can interact with you in many languages (https://benbikman.com/ben-bikmans-digital-ai-mind). In addition, our channel has first access to YouTube’s new, innovative “auto-dubbing” feature. The process currently supports translations from English into many languages, with more to come. Click on the gear icon, then choose “Audio track” to access. (Sometimes this availability is delayed several weeks or more, so check back often.) Timestamps (approximate): 02:00 – Introduction: Concussions as Metabolic Injuries 03:06 – What Happens in a Concussion 04:26 – Glucose Transport and Enzyme Inhibition After TBI 05:41 – Energy Crisis in the Brain 06:39 – Oxidative Stress and Inflammation 07:45 – Ketones as Alternative Brain Fuel 09:04 – Brain Prefers Ketones When Available 10:15 – Ketone Use After Brain Injury 11:27 – Human Study: Ketones Reach Injured Brain 12:43 – Key Benefits of Ketones for Brain Recovery 13:56 – Anti-inflammatory Effects of Ketones 15:18 – Exogenous Ketones as Preventative and Therapeutic 16:17 – Best Forms of Ketone Supplements 17:31 – NSF-Certified Ketone Supplement for Athletes 18:50 – Conclusion: Brain Fuel Flexibility IMPORTANT NOTE: The information presented is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Dr. Bikman is not a clinician—and, he is not your doctor. Always seek the advice of your own qualified health providers with questions you may have regarding medical conditions. #concussion #concussions #concussionrecovery #brainhealth #ketones #metabolichealth #braininjury #exogenousketones #goBHB #brainfuel #TBI #neuroinflammation #keto #ketoathletes #ATP #brainenergy #mitochondria #metabolicscience #BenBikman #metabolicclassroom #ketogenicdiet #ketonesforhealing Exogenous ketones—especially beta-hydroxybutyrate (BHB), the most effective and bioavailable form—can provide an immediate and practical energy source for the brain and body, particularly during times of increased demand. A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code BEN10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Ben’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/1BA884 Ben’s favorite meal-replacement shake: https://gethlth.com (discount: BEN10) Ben’s favorite allulose source: https://rxsugar.com (discount: BEN20) Ben’s favorite health check-up for men: https://blokes.co/drben15 (discount: DRBEN15)


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