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Curated by: Khan Academy India - English (11 videos)
The Gabriel phthalimide synthesis is a reaction that provides a reliable way to prepare primary amines using phthalimide as a starting material. With its selective alkylation and easy-to-follow steps, the Gabriel synthesis is a cornerstone of amine preparation in organic chemistry. Let’s uncover how this method works and why it is such a powerful tool to prepare primary amines! Courses on Khan Academy are always 100% free. Start practicing—and saving your progress—now! https://www.khanacademy.org/science/class-12-chemistry-india/x6a5fb67b43bb54b9:amines Timestamps: 00:40 - Overview of Gabriel phthalimide synthesis. 01:58 - Why was alkylation such a big disappointment? 03:57 - Why was there no risk of overalkylation in Gabriel synthesis? 05:31 - Mechanism of Gabriel phthalimide synthesis. 08:02 - More into basic hydrolysis mechanism. 08:53 - Alternate ways of opening up the phthalimide ring. 09:45 - Summary. Khan Academy India is a nonprofit organization with the mission of providing a free, world-class education for anyone, anywhere. We have videos and exercises that have been translated into multiple Indian languages, and 15 million people around the globe learn on Khan Academy every month. Support Us: https://india.khanacademy.org/donate Created by Revathi Ramachandran